The Endocrine Connoisseur
Cy. Tell us a bit about yourself. What initially piqued your interest
in working out?
I had always weight trained since I was 6 years old but in a rather
sporadic fashion. I had always admired, as many have, the physique
of "The Oak." Anyhow, while I was in 8th grade (14 years
old) my older brother had just finished high school and was starting
college. Anyhow, over the years he had developed quite a physique
by lifting on a consistent basis. He was around 6'2" 225
pounds at 10% body fat. Which, wasn't bad for someone who's all
natural and didn't use one supplement. So, I began to train with
him. He trained with me for the span of a year and then sort of
fell out of the whole "lifting" thing, focusing more
on school. He's one hell of a smart guy. I've been called boy
genius but my brother was implementing some of today's "revolutionary"
nutrition and training strategies way back when. Anyhow, from
the age of 14 and on I began lifting on a regular basis.
old are you now?
I can't even offer you a Duvel legally! How did you get such an
amazing science background at such a young age?
Again, this stems from my siblings. My sister and brother are
both have doctorates in Pharmaceutical Science. I also have a
doctor in the family who essentially became my best friend from
the age of 14 and on. Anyhow, they always had physiology, nutrition,
biochemistry, pharmacology, and various other texts of that nature
around so I began to read them. I loved the information and would
read each for hours upon hours. I then began to apply my knowledge
to body building. Keep in mind that the text I used were from
graduate programs so that is why I'm considered so "advanced"
for my age. I also had these very intelligent individuals assisting
me. If I had a question, they'd explain. By the way, I have to
give a shot out to my big bro, D.J. We sure have long names in
this family don't we (laughs)?! He just graduated last May with
his Ph.D. in pharmaceutical science and was second in his class
with a 3.975 GPA, and was also nationally recognized. Can you
imagine how great it would be if he had the same interest in bodybuilding
as I do?
did you do your first article and what was it on?
It was about March of 2000 and it was on fructose. It was for
Testosterone magazine. I had always thought fructose was unjustly
bashed in the bodybuilding community as people assumed that it
would "make you fat." The funny thing about the body
building industry is that people will hear something and take
it as though it were God's word without ever trying it out themselves.
training/nutrition publications have you been published in?
Let's see, Ironman, Testosterone ,and unbeknownst to me, Planet
Muscle a few months back. Oh and of course Shapeshifter. (smiles)
There have been blurbs written about me in other mags however.
let's get down to business. Hormones have always been a hot topic
both in the bodybuilding and athletic arenas. Prohormones especially
have come a long way in the past few years. It's pretty amazing
that we actually have over the counter products now that will
exert anabolic effects with no direct estrone or estradiol conversion.
Up until now, 4-androstenediol and 19-norandrostenediol have pretty
much been the only two worth paying any attention to. Are there
any new, exciting developments on the prohormone front? I've heard
rumors of a DHT analogue possibly being released in the near future.
Any truth behind this rumor?
Honestly, I don't know for sure. I'm only aware of one compound
that could be very exciting and it's supposed to be included along
with 4-AD-EC in the Mag-10 formula by Biotest. All I know is that
it binds very well to the AR (androgen receptor). It could be
an awesome formula.
do you think of the new 1-AD that Ergopharm is promoting so heavily?
I heard the first batches were actually 1-androstenedione and
that they've now finally switched to 1-androstenediol. What would
be the primary differences as far as the mechanisms of action
with these two prohormones?
I don't think either is intrinsically active. The only one worth
using would be 1-androstenediol.
heard that Biotest has opted to discontinue production of the
Nandrosol spray 19-norandrostenediol. Any idea why they're keeping
the Androsol but not the Nandrosol?
I can't say for sure, but I'm guessing it's simply because the
cost is too high to manufacture and the sales aren't doing well.
If a company is losing money, they should pull the product. Simple.
As to why they kept Androsol, well it's cheaper to make and I
also think it sells much better because it has gained a better
reputation in terms of being able to "feel" its effects.
the scoop on the new 4-AD-EC prohormone that Bill Roberts recently
developed? What does it stand for? What is the mechanism of action?
Why is the duration of activity so much greater than plain old
4-AD is simply the 4-androstenediol and the EC stands for Ethyl
Carbonate. This is basically an ether molecule being added to
the compound to increase oral bioavailability. It's so much greater
because adding the EC allows for a much higher blood concentration.
It basically "protects" the hormone from being metabolized
to a good extent and thus more of the active ingredient enters
the blood stream.
the newer prohormones have alleviated much cause for concern over
aromatization (the conversion of testosterone to estrogen) issues,
I realize that certain androgens may cause hair loss even though
DHT takes most of the bad rap for this problem. Are there any
hair loss issues associated with the use of certain prohormones?
I can't say that there would be. I mean we'll have to see in terms
of the pro-hormone that binds to the AR (androgen receptor), but
I doubt any other would have such deleterious effects on the hairline.
the fastest, cheapest way for a guy to test his testosterone and
estrogen levels? Are those mail order saliva tests fairly accurate?
Can you also test thyroid levels this way?
I'd say the fastest and cheapest are saliva tests. Yes, they can
be somewhat accurate if done correctly. I haven't seen any kits
that are able to test thyroid hormone levels. I'm not too sure
if it's even possible anyhow.
heard that a prohormone product cannot be truly cool unless the
product is named after a steroid and packaged in a witty-wanna-be-pseudo-steroid
container. Is there any truth to this? Uhhhh, on second thought,
skip that question. Okay! Well, moving on...
Sounds good. (laughs)
hot topic these days seems to be pro-neurotansmitter supplements
otherwise referred to as nootropics. Can you tell us about a few
of the popular neurotransmitter precursors and what they're good
for other than getting through a bad hangover? (laughs)
Tyrosine, DMAE, Phosphatidylcholine are all great "precursors"
to the important neurotransmitters, dopamine, norepinephrine,
epinephrine, aceytlcholine, etc. They can also be useful to treat
symptoms of depression or when coming off of T3 or some type of
beta 2 agonist like ephedrine. They're great for improving focus,
memory, and in general cognitive function. I'd say that most people
don't have optimal levels of these neurotransmitters so supplementation
is always a bonus. As a side note, most of the herbal "nootropics"
and even piracetam all exert their effects by increasing at least
one or all of these neurotransmitters and a few increase blood
flow thus resulting in more oxygen getting to the brain as well
as increased ATP synthesis.
for your time Cy. This is truly good stuff. Until next time.
My pleasure Arik. I look forward to it.